Cell cycle co-ordination in embryo cloning by nuclear transfer

Exciting new opportunities in embryo cloning have been made possible by recent studies on the interaction of the donor nucleus with the recipient cytoplasm after embryo reconstruction. This article reviews information regarding the co-ordination of nuclear and cytoplasmic events during embryo reconstruction, in particular the direct and indirect effects of maturation/ meiosis/mitosis-promoting factor (MPF), upon the transferred nucleus. This will be discussed in relation to DNA replication, the maintenance of correct ploidy, the occurrence of chromosomal abnormalities and development of reconstructed embryos. Although this review is primarily concerned with the reconstruction of mammalian embryos, specific examples from amphibians will also be cited.

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				D. Shi, F. Lu, Y. Wei, K. Cui, S. Yang, J. Wei, and Q. Liu Buffalos (Bubalus bubalis) Cloned by Nuclear Transfer of Somatic Cells Biol Reprod, August 1, 2007; 77(2): 285 - 291. [Abstract] [Full Text] [PDF]

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				R. Blelloch, Z. Wang, A. Meissner, S. Pollard, A. Smith, and R. Jaenisch Reprogramming Efficiency Following Somatic Cell Nuclear Transfer Is Influenced by the Differentiation and Methylation State of the Donor Nucleus Stem Cells, September 1, 2006; 24(9): 2007 - 2013. [Abstract] [Full Text] [PDF]

				H.-T. Bui, N. Van Thuan, T. Wakayama, and T. Miyano Chromatin remodeling in somatic cells injected into mature pig oocytes. Reproduction, June 1, 2006; 131(6): 1037 - 1049. [Abstract] [Full Text] [PDF]

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				X. Li, Y. Dai, and W.R. Allen Influence of Insulin-Like Growth Factor-I on Cytoplasmic Maturation of Horse Oocytes In Vitro and Organization of the First Cell Cycle Following Nuclear Transfer and Parthenogenesis Biol Reprod, October 1, 2004; 71(4): 1391 - 1396. [Abstract] [Full Text] [PDF]

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				T. Tani, Y. Kato, and Y. Tsunoda Reprogramming of Bovine Somatic Cell Nuclei Is Not Directly Regulated by Maturation Promoting Factor or Mitogen-Activated Protein Kinase Activity Biol Reprod, December 1, 2003; 69(6): 1890 - 1894. [Abstract] [Full Text] [PDF]

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				J.-L. Liu, L.-Y. Sung, M. Barber, and X. Yang Hypertonic Medium Treatment for Localization of Nuclear Material in Bovine Metaphase II Oocytes Biol Reprod, May 1, 2002; 66(5): 1342 - 1349. [Abstract] [Full Text]

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				C.L. Keefer, R. Keyston, A. Lazaris, B. Bhatia, I. Begin, A.S. Bilodeau, F.J. Zhou, N. Kafidi, B. Wang, H. Baldassarre, et al. Production of Cloned Goats after Nuclear Transfer Using Adult Somatic Cells Biol Reprod, January 1, 2002; 66(1): 199 - 203. [Abstract] [Full Text]

				L. Lai, T. Tao, Z. Machaty, B. Kuhholzer, Q.-Y. Sun, K.-W. Park, B. N. Day, and R. S. Prather Feasibility of Producing Porcine Nuclear Transfer Embryos by Using G2/M-Stage Fetal Fibroblasts as Donors Biol Reprod, November 1, 2001; 65(5): 1558 - 1564. [Abstract] [Full Text] [PDF]

				P. Kasinathan, J. G. Knott, P. N. Moreira, A. S. Burnside, D. Joseph Jerry, and J. M. Robl Effect of Fibroblast Donor Cell Age and Cell Cycle on Development of Bovine Nuclear Transfer Embryos In Vitro Biol Reprod, May 1, 2001; 64(5): 1487 - 1493. [Abstract] [Full Text]

				C.L. Keefer, H. Baldassarre, R. Keyston, B. Wang, B. Bhatia, A.S. Bilodeau, J.F. Zhou, M. Leduc, B.R. Downey, A. Lazaris, et al. Generation of Dwarf Goat (Capra hircus) Clones Following Nuclear Transfer with Transfected and Nontransfected Fetal Fibroblasts and In Vitro-Matured Oocytes Biol Reprod, March 1, 2001; 64(3): 849 - 856. [Abstract] [Full Text]

				T. Tani, Y. Kato, and Y. Tsunoda Direct Exposure of Chromosomes to Nonactivated Ovum Cytoplasm Is Effective for Bovine Somatic Cell Nucleus Reprogramming Biol Reprod, January 1, 2001; 64(1): 324 - 330. [Abstract] [Full Text]

				B. Kühholzer and R. S. Prather Advances in Livestock Nuclear Transfer Experimental Biology and Medicine, September 1, 2000; 224(4): 240 - 245. [Abstract] [Full Text]

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				H. Liu, C.-W. Wang, J. A. Grifo, L. C. Krey, and J. Zhang Reconstruction of mouse oocytes by germinal vesicle transfer: maturity of host oocyte cytoplasm determines meiosis Hum. Reprod., September 1, 1999; 14(9): 2357 - 2361. [Abstract] [Full Text] [PDF]

				T. Dominko, M. Mitalipova, B. Haley, Z. Beyhan, E. Memili, B. McKusick, and N. L. First Bovine Oocyte Cytoplasm Supports Development of Embryos Produced by Nuclear Transfer of Somatic Cell Nuclei from Various Mammalian Species Biol Reprod, June 1, 1999; 60(6): 1496 - 1502. [Abstract] [Full Text]

				T. Takeuchi, B. Ergun, T. H. Huang, Z. Rosenwaks, and G. D. Palermo A reliable technique of nuclear transplantation for immature mammalian oocytes Hum. Reprod., May 1, 1999; 14(5): 1312 - 1317. [Abstract] [Full Text] [PDF]

				D. N. Wells, P. M. Misica, and H. R. Tervit Production of Cloned Calves Following Nuclear Transfer with Cultured Adult Mural Granulosa Cells Biol Reprod, April 1, 1999; 60(4): 996 - 1005. [Abstract] [Full Text]

				A. C. Boquest, B. N. Day, and R. S. Prather Flow Cytometric Cell Cycle Analysis of Cultured Porcine Fetal Fibroblast Cells Biol Reprod, April 1, 1999; 60(4): 1013 - 1019. [Abstract] [Full Text]

				D. P. Wolf, L. Meng, N. Ouhibi, and M. Zelinski-Wooten Nuclear Transfer in the Rhesus Monkey: Practical and Basic Implications Biol Reprod, February 1, 1999; 60(2): 199 - 204. [Abstract] [Full Text] [PDF]